This annual report highlights Youth RISE’s key achievements throughout the year, including advocating for full-spectrum harm reduction (FSHR) and human rights at the 68th Session of the CND, embedding youth priorities into the 2026–2031 Global AIDS Strategy, co-leading youth consultations with the Global Commission on Drug Policy (GCDP), and launching landmark educational tools such as “The Advocacy Playground” curriculum. Through peer-led leadership, capacity building, and international working group engagements, the report demonstrates how young people who use drugs (YPWUD) continue to drive transformative change and demand meaningful inclusion at decision-making tables worldwide.